A Biochemistry Lesson
Guests: Doug Sharp and Rich Geer
Description: An explanation how complex bonding of molecules in proteins causes them to fold up into a three dimensional shape that facilitates it to perform active functions in life. Proteins are made up of amino acids, and each of the 20 amino acids have an amine group and an acid group where they form the peptide bond. The peptide bond requires the removal of water, which is what life does automatically, but it creates problems for those who want to emulate the origin of life. Each amino acid has a side chain that gives it a personality. One may be an oily side chain that congregates together away from water, another forms disulfide bridges, others ionic bonds or Van Der Waals forces. As proteins are made in a living system there is a complex mechanism in the ribosome that shapes the protein into its useful three dimensional shape. There are millions of ways to get this wrong, but it occurs without fail in you cells.